简介：盐酸二甲双胍，Metformin (hydrochloride)是FDA批准的用于治疗2型糖尿病的一线药物。 二甲双胍主要是通过对线粒体呼吸链复合物1的轻度和短暂抑制降低肝脏葡萄糖的产生。
盐酸二甲双胍物理化学性质：
|
沸点 |
224.1ºC at 760 mmHg |
|
熔点 |
223-226 °C(lit.) |
|
分子式 |
C4H12ClN5 |
|
分子量 |
165.625 |
|
闪点 |
89.3ºC |
|
精确质量 |
165.078125 |
|
PSA |
88.99 |
|
LogP |
1.0585 |
|
外观性状 |
结晶固体 |
|
蒸汽压 |
0.0929mmHg at 25°C |
|
储存条件 |
储存在阴凉，干燥的地方 |
|
稳定性 |
常温常压下稳定，避免强氧化物 接触 |
盐酸二甲双胍详细介绍：
|
中文名称： |
盐酸二甲双胍 |
|
中文别名： |
盐酸二甲双胍;1,1-二甲基双胍盐酸盐;二甲双胍盐酸盐;甲福明二甲双胍盐酸盐;甲福明二甲双胍盐酸;甲福明二甲双胍;盐酸二甲双胍对照品;3,6-二氢-4-氰基-2H-吡喃;Metformin Hydrochloride 二甲双胍盐酸盐;二甲双胍;磷酸肌酸钠;欧洲版盐酸二甲双胍;盐酸苯乙双胍;盐酸二甲双;盐酸二甲双胍 EP标准品;盐酸二甲双胍 USP标准品;盐酸二甲双胍 标准品;盐酸二甲双胍盐酸二甲双胍;盐酸二甲双胍杂质;盐酸二甲双胍杂质对照品;盐酸二氧丙嗪;盐酸盐二甲双胍 标准品;降血糖药;南箭牌;桶;甲福明 盐酸盐;[ "盐酸二甲双胍", " Metformin hydrochloride" ] |
|
英文名称： |
Metformin |
|
英文别名： |
Metformin HCL;Metformin Hydrochloride;3-(diaminomethylidene)-1,1-dimethylguanidine hydrochloride (1:1);1,1-dimethylbiguanide hydrochloride;1,1-Dimethylbiguanide hydrochloride (Metformin);Metformin hydrochloride (Apophage®, Orabet®, Riomet®, Walaphage®, Diabex®, Melbin®, Diaformin®, Fornidd®, Glucoformin®, Glucophage®);Metformin (hydrochloride);Metformin Hydrochlor;Metformin hydrochloride solution;Metformin hydrochloride;N1,N1-Dimethylbiguanide hydrochloride;1,1-Dimethylbiguanide hydrochloride,Metformin;3-(diaminomethylidene)-1,1-dimethylguanidine,hydrochloride;metformin;1,1-Dimethylbiguanide;N,N-dimethylimidodicarbonimidic diamide;Metiguanide;Dimethylbiguanide;Glucophage;Haurymelin;Glumetza;Gliguanid;Fluamine;Flumamine;Melbin;Diabex;N,N-Dimethylbiguanide;Metformina;Metforminum;Metformine;Glifage;Islotin;Siofor;N1,N1-Dimethylbiguanide;DMGG;NNDG;Dimethyldiguanide;N,N-Dimethyldiguanide;Metformina [DCIT];Imidodicarbonimidic diamide, N,N-dimethyl-;Metformina [Spanish];Metforminum [INN-Latin];Metformine [INN-French];Metformin [USAN:INN:BAN];1,1-Dim |
|
CAS号： |
1115-70-4 |
|
分子式： |
C4H11N5 |
|
分子量： |
129.16 |
|
详细描述： |
创赛优选提供1115-70-4，盐酸二甲双胍，Metformin HCl，Medlife，上海现货。 Medlife，致力于提供高品质、高性价比小分子化合物的产品。 Medlife小分子化合物大量库存，提供超过2万种的抑制剂、激动剂、拮抗剂等产品，是药物及疾病研究的重要原料供应商。 抗糖尿病药物，Metformin (hydrochloride) 是FDA批准的用于治疗2型糖尿病的一线药物。 二甲双胍主要是通过对线粒体呼吸链复合物1的轻度和短暂抑制降低肝脏葡萄糖的产生。 查询关键词:“1115-70-4，盐酸二甲双胍，Metformin HCl，PC14944，Medlife，上海现货”。 |
盐酸二甲双胍参考文献：
[1]. Soraya H, et al. Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.
[2]. Quaile MP, et al. Toxicity and toxicokinetics of metformin in rats. Toxicol Appl Pharmacol. 2010 Mar 15;243(3):340-7.
[3]. Xue J, et al. Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a possible role in the treatment of adenomyosis. Reproduction. 2013 Aug 21;146(4):397-406.
[4]. Otto M, et al. Metformin inhibits glycogen synthesis and gluconeogenesis in cultured rat hepatocytes. Diabetes Obes Metab. 2003 May;5(3):189-94.
[5]. Avci CB, et al. Therapeutic potential of an anti-diabetic drug, metformin: alteration of miRNA expression in prostate cancer cells. Asian Pac J Cancer Prev. 2013;14(2):765-8.
[6]. Nie L, et al. The Landscape of Histone Modifications in a High-Fat Diet-Induced Obese (DIO) Mouse Model. Mol Cell Proteomics. 2017 Jul;16(7):1324-1334.
[7]. Zhang D, et al. Metformin ameliorates BSCB disruption by inhibiting neutrophil infiltration and MMP-9 expression but not direct TJ proteins expression regulation. J Cell Mol Med. 2017 Jul 12.
| 货号 | 产品名称 | 品牌 | 规格型号 | 包装 | 目录价 | 促销价 | 数量 | 购物车 |
|---|---|---|---|---|---|---|---|---|
| Alfa-R12054 | [Alfa Aesar]盐酸二甲双胍，1000ppm ,1115-70-4 | Alfa Aesar | 1ml | ¥945.00 | ¥945.00 |
|
||
| Alfa-R11010 | [Alfa Aesar]盐酸二甲双胍标准溶液，100ppm ,1115-70-4 | Alfa Aesar | 1ml | ¥450.00 | ¥450.00 |
|
||
| PC14944 | 盐酸二甲双胍. ,1115-70-4 | Medlife | ≥98% | 10mM (in 1mL DMSO) | ¥780.00 | ¥780.00 |
|
|
| PC14944 | 盐酸二甲双胍. ,1115-70-4 | Medlife | ≥98% | 10g | ¥780.00 | ¥780.00 |
|
|
| PC14944 | 盐酸二甲双胍. ,1115-70-4 | Medlife | ≥98% | 50g | ¥1872.00 | ¥1872.00 |
|
|
| PC14944 | 盐酸二甲双胍. ,1115-70-4 | Medlife | 97% | 5g | ¥39.00 | ¥39.00 |
|
|
| A03-B1970 | [APExBIO]Metformin HCl,98% ,1115-70-4 | APExBIO | 98% | 10mM | ¥500.00 | ¥500.00 |
|
|
| A03-B1970 | [APExBIO]Metformin HCl,98% ,1115-70-4 | APExBIO | 98% | 10g | ¥500.00 | ¥500.00 |
|
|
| A03-B1970 | [APExBIO]Metformin HCl,98% ,1115-70-4 | APExBIO | 98% | 50g | ¥1200.00 | ¥1200.00 |
|
|
| PA58464 | 盐酸二甲双胍 ,1115-70-4 | PERFEMIKER | 97% | 5g | ¥41.00 | ¥41.00 |
|
|
| PA58464 | 盐酸二甲双胍 ,1115-70-4 | PERFEMIKER | 97% | 25g | ¥65.00 | ¥65.00 |
|
|
| PA58464 | 盐酸二甲双胍 ,1115-70-4 | PERFEMIKER | 97% | 100g | ¥102.00 | ¥102.00 |
|
|
| PA58464 | 盐酸二甲双胍 ,1115-70-4 | PERFEMIKER | 97% | 500g | ¥347.00 | ¥347.00 |
|
|
| PA58464 | 盐酸二甲双胍 ,1115-70-4 | PERFEMIKER | 97% | 2.5kg | ¥1385.00 | ¥1385.00 |
|
|
| SIGMA-BP227 | [Sigma-Aldrich]Metformin Hydrochloride ,1115-70-4 | Sigma-Aldrich | 1EA | ¥2708.85 | ¥2708.85 |
|
||
| SIGMA-M0605000 | [Sigma-Aldrich]Metformin Hydrochloride ,1115-70-4 | Sigma-Aldrich | 1EA | ¥2506.96 | ¥2506.96 |
|
||
| SIGMA-PHR1084 | [Sigma-Aldrich]Metformin Hydrochloride ,1115-70-4 | Sigma-Aldrich | 500MG | ¥1056.61 | ¥1056.61 |
|
||
| Sigma-D150959 | [Sigma-Aldrich]盐酸二甲双胍 ,1115-70-4 | Sigma-Aldrich | 97% | 5G | ¥1489.14 | ¥1489.14 |
|
|
| 01008499 | [Adamas]盐酸二甲双胍 ,1115-70-4 | Adamas | 98%+ | 500g | ¥273.00 | ¥273.00 |
|
|
| 01008498 | [Adamas]盐酸二甲双胍 ,1115-70-4 | Adamas | 98%+ | 100g | ¥105.00 | ¥105.00 |
|
|
| 01008497 | [Adamas]盐酸二甲双胍 ,1115-70-4 | Adamas | 98%+ | 25g | ¥54.00 | ¥54.00 |
|
|
| S30880 | [源叶]盐酸二甲双胍 ,1115-70-4 | 源叶 | 98% | 25g | ¥45.00 | ¥45.00 |
|
|
| S30880 | [源叶]盐酸二甲双胍 ,1115-70-4 | 源叶 | 98% | 100g | ¥90.00 | ¥90.00 |
|
|
| S30880 | [源叶]盐酸二甲双胍 ,1115-70-4 | 源叶 | 98% | 500g | ¥270.00 | ¥270.00 |
|
|
| B25331 | [源叶]盐酸二甲双胍 ,1115-70-4 | 源叶 | HPLC≥98% | 250mg | ¥400.00 | ¥400.00 |
|
|
| B25331 | [源叶]盐酸二甲双胍 ,1115-70-4 | 源叶 | HPLC≥98% | 1g | ¥1200.00 | ¥1200.00 |
|
|
| M2009 | [TCI]二甲双胍盐酸盐 (LC&T) ,1115-70-4 | TCI | ≥98% | 100g | ¥98.00 | ¥98.00 |
|
|
| M2009 | [TCI]二甲双胍盐酸盐 (LC&T) ,1115-70-4 | TCI | ≥98% | 25g | ¥98.00 | ¥98.00 |
|
|
| A14956000ME | [DR.E]盐酸二甲双胍 ,1115-70-4 | Dr.E | 100 µg/mL in Methanol | 1ml | ¥133.00 | ¥133.00 |
|
|
| C14956000 | [DR.E]盐酸二甲双胍 ,1115-70-4 | Dr.E | 纯品型 | 250mg | ¥1258.00 | ¥1258.00 |
|
|
| MACKLIN-M813341 | 盐酸二甲双胍 ,1115-70-4 | macklin | 97% | 25g | ¥35.00 | ¥35.00 |
|
|
| MACKLIN-M813341 | 盐酸二甲双胍 ,1115-70-4 | macklin | 97% | 5g | ¥29.00 | ¥29.00 |
|
|
| MACKLIN-M813341 | 盐酸二甲双胍 ,1115-70-4 | macklin | 97% | 100g | ¥58.00 | ¥58.00 |
|
|
| MACKLIN-M813341 | 盐酸二甲双胍 ,1115-70-4 | macklin | 97% | 500g | ¥252.00 | ¥252.00 |
|
|
| MACKLIN-M813341 | 盐酸二甲双胍 ,1115-70-4 | macklin | 97% | 2.5kg | ¥1060.00 | ¥1060.00 |
|
|
| RHAWN-R000310 | 盐酸二甲双胍 ,1115-70-4 | 罗恩 | 97% | 25g | ¥34.00 | ¥34.00 |
|
|
| RHAWN-R000310 | 盐酸二甲双胍 ,1115-70-4 | 罗恩 | 97% | 5g | ¥28.00 | ¥28.00 |
|
|
| RHAWN-R000310 | 盐酸二甲双胍 ,1115-70-4 | 罗恩 | 97% | 500g | ¥242.00 | ¥242.00 |
|
|
| RHAWN-R000310 | 盐酸二甲双胍 ,1115-70-4 | 罗恩 | 97% | 100g | ¥56.00 | ¥56.00 |
|
|
| RHAWN-R000310 | 盐酸二甲双胍 ,1115-70-4 | 罗恩 | 97% | 2.5kg | ¥1018.00 | ¥1018.00 |
|
|
| A-M107827 | 二甲双胍盐酸盐 ,1115-70-4 | Aladdin阿拉丁 | 97% | 5g | ¥29.00 | ¥29.00 |
|
|
| A-M107827 | 二甲双胍盐酸盐 ,1115-70-4 | Aladdin阿拉丁 | 97% | 100g | ¥89.00 | ¥89.00 |
|
|
| A-M107827 | 二甲双胍盐酸盐 ,1115-70-4 | Aladdin阿拉丁 | 97% | 25g | ¥46.00 | ¥46.00 |
|
|
| A-M107827 | 二甲双胍盐酸盐 ,1115-70-4 | Aladdin阿拉丁 | 97% | 500g | ¥258.00 | ¥258.00 |
|
|
| A-M276594 | 盐酸二甲双胍（mM / ml） ,1115-70-4 | Aladdin阿拉丁 | ≥99% | 100mM/ml | ¥240.00 | ¥240.00 |
|
|
| TX81129 | 盐酸二甲双胍 ,1115-70-4 | 颖心实验室 | 0.97 | 100g | ¥280.00 | ¥280.00 |
|
|
| TX81129 | 盐酸二甲双胍 ,1115-70-4 | 颖心实验室 | 0.97 | 25g | ¥120.00 | ¥120.00 |
|
|
| TX81129 | 盐酸二甲双胍 ,1115-70-4 | 颖心实验室 | 0.97 | 500g | ¥680.00 | ¥680.00 |
|
|
| TRC-M258815 | [TRC]药物标准品Metformin Hydrochloride ,1115-70-4 | TRC | 1g | ¥671.00 | ¥671.00 |
|
||
| TRC-M258815 | [TRC]药物标准品Metformin Hydrochloride ,1115-70-4 | TRC | 10g | ¥1342.00 | ¥1342.00 |
|
||
| TRC-M258815 | [TRC]药物标准品Metformin Hydrochloride ,1115-70-4 | TRC | 5g | ¥732.00 | ¥732.00 |
|
沪公网安备31011402010659号
